PATHOLOGY

The continuation of the funded position of Prof Anthony Gill (0.3FTE) remains crucial for the ongoing development and use of the Formalin Fixed Paraffin Embedded (FFPE) tumour bank. This project links all patients with frozen material in the Kolling tumour bank to matched paraffin blocks and then expands this resource by retrieving large numbers of paraffin blocks of similar tumours for use in validation studies.

Tumour streams are now numerous and highly annotated (e.g. we have now linked to long-term follow-up over 3,000 patients with colorectal cancer, 600 patients with glioblastoma multiforme, 150 patients with medullary thyroid carcinoma, 600 patients with papillary thyroid carcinoma, and 100 patients with adrenal cortical carcinoma) and have been the basis of major international collaborations including the Cancer Genome Atlas (TCGA).

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