Dr Wei Deng received her PhD in Chemistry with the background in the area of nanotechnology at Macquarie University in 2011 and received an ARC DECRA Fellowship in 2012. Dr Deng has worked at Macquarie University from April 2013 to June, 2018 as a Research Fellow. Currently she is conducting her research at UNSW as a senior Research Fellow.

 

Research Interests

Her research focuses on the development of nanocarriers incorporating drug/gene for cancer diagnostics. In particular, She has led the projects on development of diverse triggerable nanomaterials for cancer treatments, including an X-ray (or light) triggered liposomal delivery platform and light-triggered polymer nanocarriers for enhanced photodynamic therapy. These engineered gene/drug delivery systems are now a major strength of her research profile, attracting internal, cross-disciplinary and industry collaborations.

“Exploring a novel nanotechnology strategy for the neo-adjuvant treatment of rectal cancer by photodynamic therapy and ionising radiation”

Colorectal Surgical Society of Australia and New Zealand Foundation Research 2017

Year Award/ Honour Institution
2017 Ramsay Research and Teaching Fund – Project Award “Nanotechnology strategy for enhanced photodynamic therapy” Ramsay Healthcare 
2013 Discovery Early Career Researcher Award “Nanolamps: Unlocking targeted gene silencing in deep tissue with nanoparticle-based light sources” Australian Research Council 
2010 Deputy Vice Chancellor’s Commendation Award Macquarie University

F Xie, W Deng, and Ewa M. Goldys, “Compatibility of Metal –Induced Fluorescence Enhancement with Applications in Analytical Chemistry and Biosensing” in the book “Surface Plasmon Enhanced, Coupled and Controlled Fluorescence” edited by Chris D. Geddes (ISBN: 978-1-118-02793-6) by Wiley, 2017 [More Information]

W Deng*, W Chen, S Clement, A Guller, Z Zhao, A Engel and E Goldys, Controlled gene and drug release from a liposomal delivery platform triggered by X-ray radiation, in press, Nature Communications [More Information]

S Clement, W Chen, W Deng, E Goldys, Folic acid conjugated biodegradable nanoconstructs for targeted deep tumour therapy, International Journal of Nanomedicine 2018:13, 3553–3570 [More Information]

W Chen, W Deng*, EM Goldys, Light-triggerable liposomes for enhanced endo/lysosomal escape and gene silencing in PC12 cells, Molecular Therapy – Nucleic Acids, 2017, DOI: 10.1016/j.omtn.2017.04.015 [More Information]

Kautzka, S. Clement, EM. Goldys, W. Deng*, Light-triggered liposomal cargo delivery platform incorporating photosensitizers and gold nanoparticles for enhanced singlet oxygen generation and increased cytotoxicity, International journal of nanomedicine, 2017, 12, 969-977 [More Information]

Clement, M. Sobhan, W. Deng, E. Camilleri, E. Goldys, Nanoparticle-mediated singlet oxygen generation from photosensitizers, J. Photochemistry and Photobiology A: Chemistry, 2017, 332, 66–71 [More Information]

W Deng*, Z. Kautzka, W. Chen, E. Goldys,  PLGA nanocomposites loaded with verteporfin and gold nanoparticles for enhanced photodynamic therapy on cancer cells, RSC Advances, 2016, 6, 112393-112402 [More Information]

Deng*, M. M. Farnham, E. M Goldys, S. Mohammed, P. M Pilowsky, Gene interference with morpholinos in a gold nanoparticle-based delivery platform in rat PC12 cells, J. Biomedical Nanotechnology, 2015, 11, 2111-2123 [More Information]

Clement, W. Deng, E. Camilleri, B. Wilson, E. Goldys, X-ray induced singlet oxygen generation by nanoparticle-photosensitizer conjugates for photodynamic therapy: determination of singlet oxygen quantum yield, Scientific Reports, 2016, 6:19954 [More Information]

Deng, E. M Goldys, M. MJ Farnham, P. M. Pilowsky, Optogenetics, the intersection between physics and neuroscience: Light stimulation of neurons in physiological conditions, Am J Physiol Regul Integr Comp Physiol, 2014 307: R1292–R1302. [More Information]

Deng* and E, Goldys, Chemical sensing with nanoparticles as optical reporters: from noble metal nanoparticles to quantum dots and upconverting nanoparticles, Analyst, 2014, 139, 5321 – 5334. [More Information]

S Clement, W. Deng, K. Drozdowicz-Tomsia, D. Liu, C. Zachreson, E. Goldys, Bright, water-soluble CeF3 photo-, cathodo-, and X-ray luminescent nanoparticles, J Nanopart Res, 2014, 17:7, DOI: 10.1007/s11051-014-2833-0 [More Information]

Zhang, X. Zheng, W. Deng, Y. Lu, S Lechevallier, Z. Ye, E. Goldys, J. Dawes, J. Piper, J. Yuan, M. Verelst, D. Jin, Practical implementation, characterization and applications of a multi-colour time-gated luminescence microscope, Scientific Reports, 2014, 4: 6597, DOI: 10.1038/srep06597 [More Information]

Deng, F. Xie, H. T. M. C. M. Baltarac, E. M. Goldys, Metal-enhanced fluorescence in the life sciences: here, now and beyond, Phys. Chem. Chem. Phys., 2013, 15, 15695-15708 (Advance Article) [More Information]

For more information please contact:

Email: wei.deng@unsw.edu.au

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