The Kolling Institute Tumour Bank

Located on the Royal North Shore Hospital, the Kolling Institute Tumour Bank (KITB) is a collection of human biospecimens that are stored and distributed for use in cancer research. It is partially funded by the Sydney Vital grant (2017-2019) from the Cancer Institute NSW (CINSW), supporting two of the current four positions working as part of our Tumour Bank.

The KITB consists of collections of breast, gynaecological, upper gastrointestinal, endocrine and neurological tumours. In 2017, colorectal specimens were added to this collection. There is also a Healthy Volunteers blood bank. There are currently over 20,000 specimens collected as part of the KITB from over 9,000 cancer patients who have had cancer surgery at Royal North Shore Hospital, North Shore Private or The Mater Hospital, North Sydney with approval from the relevant Human Research Ethics Committees (HRECs). This is an invaluable resource that facilitates translational research now and into the future as new technological platforms become available.

In 2017-18, the KITB is working closely with NSW Health Pathology to develop streamlined approaches to tumour banking by further embedding biobanking processes within Anatomical Pathology laboratories. The KITB is also working as part of the CINSW Biobanking Stakeholder Network on a project to explore data linkage for the clinical annotation of biospecimens.

Tumour Banking for Future Research

KITB Team (L->R): Ussha Pillai, Mikaela Holmes, Shannon Chan and Sam Yuen

The KITB is one of the oldest tumour banks established in NSW.

  • 1992 the KITB was established by Professors Bruce Robinson and Leigh Delbridge. The first collections were endocrine tumours (thyroid, parathyroid and adrenal tumours), reflecting the research interests of these professors.
  • 2001 – Professors Ross Smith and Thomas Hugh began to collect upper gastrointestinal tumours (liver, pancreas and stomach tumours).
  • 2002 – Professor Bruce Robinson and Dr Ray Cook established a collection of neurological (brain and pituitary) tumours.
  • 2004 – the KITB expanded into breast and gynaecological (ovarian, endometrial and cervical) tumour collections with the research interests of Professors Robert Baxter and Deborah Marsh, respectively.
  • 2005 – the Healthy Volunteers collection was established by Professor Deborah Marsh as a means for researchers to compare the differences between normal, healthy blood and blood from cancer patients.
  • 2006 – the KITB became a funded collection node of the Australian Breast Cancer Tissue Bank.
  • 2017 – the KITB began collecting colorectal tumours and rolled all informed consenting literature and forms under the one umbrella protocol, allowing all cancer types to be collected.

For more information please contact:

Office: (02) 9926 4771