Sydney Vital would like to congratulate A/Prof Mark Molloy from Macquarie University and his assembled investigators on their successful Cancer Institute NSW Research Equipment Grant application titled “High content oncoproteomics for improved prognostication and treatment response”.
There is increasing use of molecular markers for diagnosis, prognosis and identifying treatment response and resistance in oncology patients. Modern mass spectrometers can now generate high proteomic content of specimens, approaching the complexity commonly associated with genomic profiling. In this project we will test if high content proteomics has utility to accurately identify cancer subtypes and determine associations with survival outcomes. In a range of cancers, we will examine proteins and glycoproteins from frozen tumour tissues and from archival formalin-fixed samples. This information will help clinicians better care for cancer patients based on tumour protein markers.
The grant will contribute to the purchase of a Q Exactive HF mass spectrometer which will be located at the Australian Proteome Analysis Facility based at Macquarie University. Cancer researchers with interest to collaborate to use the equipment should contact A/Prof Molloy.